| Club | Adviser |
| Amnesty International | Yager, John |
| Animal Club | Holliday, Stacey |
| Animation Club | Zakalik, Sarah |
| Art Club | Zakalik, Sarah |
| ASI | Zoltoski, Erin |
| Best Buddies | Merrifield, Cindy |
| Bookstore | Burch, Kristie |
| Community and Service Learning | Wittig, Julie |
| DECA | Romas, Tish |
| Diversity Club | Rasmussen, Anna / Sidou, Julie |
| Drama/ Musical Club | Hawryschuk, Kelli |
| Dunegeons and Dragons | LaBarr, Paige |
| Environmental Club | Ullock, Caitlin / Smith, Karen |
| Finance & Investment | Larson, Dave |
| French Club | Topla, Francine |
| Game Development Club | Wirth, Larry |
| Girl Up! | Ark, Anne-Marie |
| GSA | Nazarian, Sarah |
| Habitat for Humanity | Peachey, Bruce |
| Harry Potter Club | Waterbury, Kim |
| Interact Club | Ullock, Caitlin |
| Library Club - Ex Libris | Otto, Kris |
| Literary Magazine | Nazarian, Sarah |
| Masterminds / Chess | Dougherty, Mark |
| Math League | Bonin, Erica |
| Military History | Rumley, Kyle |
| Mock Trial | Rumley, Kyle |
| Model UN | Yager, John |
| Morning Madness | Beck, Megan |
| Newspaper Club | O'Dell, Kristin / Curtis, Katie |
| Peer Tutoring Club | Peachey, Bruce |
| Pittsford Community Youth Services | Lennox, Jill |
| Robotics | Curry, Katherine / Profitt, Charles |
| ROC 2 Change | Gunther, Carrie |
| ROCKids Connect | O'Neill, Maureen |
| Runway for Relief | Waterbury, Kim |
| Sailing Club | Faudree, Liam |
| Science Olympiad | Smith, Steve |
| Sources of Strength | Hefner, Laura |
| Spanish Club | Spitz, Mallory |
| Students Against Cancer | Welsher, Tom |
| The Reality Check Club | Kane, Ann |
| Theater Tech Club | Beck, Megan |
| TIES | Cameron-Kody, Dale / Kane, Ann |
| Yearbook | Johnson, Mindy |
